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Explored: Beneficial effect of cucumber extract on joint health

CuberUp® may have positive impact on knee pain, mobility and muscle function

Mollet del Vallès (Spain), May 2024: Researchers have found that supplementation with Euromed’s new cucumber extract CuberUp® may be a useful natural approach to maintaining healthy joints (1). According to the double-blind clinical study, cucumber extract is linked to the relief of joint pain as well as better muscle function, thus significantly improving quality of life in people with joint discomfort. The results suggest that CuberUp® is a promising botanical ingredient for applications targeting Healthy Agers, athletes and others affected by joint problems.
Joint discomfort, which can vary in severity with conditions such as osteoarthritis, is a common problem that can impact day-to-day living and overall quality of life, particularly among adults over 40. A recent eight-week randomized, double-blind placebo-controlled trial, focused on adults with varying degrees of joint discomfort of the knee. The 55 participants received a daily supplement containing 20 mg of Euromed’s new natural cucumber extract (Cucumis sativus L.).


Subjective perception of knee pain improved significantly in both study groups, but improvements were higher in the CuberUp® group. In addition, a reduction in pain and stiffness, together with improved physical function, were significantly more pronounced in those receiving the cucumber extract. The Timed Up and Go test result – a clinical method to assess a patient’s mobility and risk of falling – also decreased considerably in the experimental group. Plus, the researchers noted an improvement in muscle function during knee flexion exercises. Furthermore, they found that inflammatory and cartilage degradation
biomarkers decreased significantly in patients supplemented with CuberUp®.


1 Pérez-Piñero, S. et al.: Effectiveness of a Cucumber Extract Supplement on Articular Pain in Patients with Knee
Osteoarthritis: A Randomized Double-Blind Controlled Clinical Trial. Appl. Sci. 2023, 13, 485.
https://doi.org/10.3390/app13010485

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