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Articles

Welcome to the Articles section of Nutramedic&Cosmetics, a rich repository of articles that delve into the many facets of the food supplements and cosmetics industry.

Our “Articles” section features a wide range of topics, providing you with in-depth knowledge and insights. From the latest scientific research in food supplements to the newest trends in cosmetics, our articles cover it all. They are written by industry experts and thought leaders, ensuring you get accurate and reliable information.

STUDY: Gencor’s Levagen®+ Demonstrates Significant Support to Ease Menstrual Discomfort

 Gencor has announced the publication of its recent human clinical study investigating its palmitoylethanolamide (PEA) ingredient, Levagen®+, to be a safe, innovative, and effective supplement to ease acute menstrual discomfort. Menstrual pain, or primary dysmenorrhea (menstrual pain without any underlying pathology), is the most common gynecological condition among women of reproductive age. It is estimated to be the leading cause of chronic pelvic pain globally (World Health Organization). The prevalence rate ranges from 45 to 95% and is linked to restrictions in daily activities, work and school absenteeism, and personal distress. While the primary mechanisms of dysmenorrhea are not fully understood, the main cause of the painful symptoms is attributed to the overproduction of uterine prostaglandins, particularly prostaglandin F2-α (PGF2α) and prostaglandin E2 (PGE2), which peak during the early days of menstruation. Besides their regulatory effects on inflammation, pain, and body temperature, prostaglandin production is also thought to contribute to secondary symptoms of menstrual pain, such as diarrhea, nausea, and vomiting. Moreover, women experiencing dysmenorrhea may show elevated levels of pro-inflammatory mediators and an increased body temperature. Preclinical research suggests that PEA’s primary mechanism of action is to provide relief from occasional discomfort and support a balanced inflammatory response, which may

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Nearly Half of Type 2 Diabetes Patients Have Micronutrient Deficiencies, New BMJ Review Finds

A new systematic review published in BMJ highlighted the fact that nearly half of patients with type 2 diabetes (T2D) experience micronutrient deficiencies, with women experiencing these deficiencies more frequently than men. Micronutrients are valuable cofactors in glucose metabolic pathways, pancreatic beta cell function, and the insulin signaling cascade, suggesting that their deficiency may contribute to the development of T2D. Micronutrients such as biotin, chromium, thiamine, vitamin D, and vitamin C may have metabolic effects on glucose metabolism. Researchers and physicians have paid little attention to the role of hidden hunger and micronutrient deficiencies in type 2 diabetes. A new systematic review and meta-analysis assessed the prevalence of various micronutrient deficiencies in the T2D patient population reported in 127 published studies (1998-2023), with 52,501 patients in total who met the inclusion and exclusion criteria. Almost half (45.30%) of the T2D population had multiple micronutrient deficiencies, and 40% of patients with diabetic complications had micronutrient deficiencies. The prevalence of vitamin D deficiency was highest (60.45%), followed by magnesium deficiency (41.95%). The next in order was vitamin B12 deficiency in a subgroup of T2D patients on metformin. . Deficiency of these micronutrients is notably prevalent among individuals who have both obesity and

Read More »

Interview Jonny Bowden, PhD Cortisol: Q and A

Consumer interest in cortisol is rising due to growing awareness about the negative effects of chronic stress on physical and mental health, as well as cortisol’s role in stress and weight gain. Elevated cortisol levels contribute to various health issues, including weight gain, immune suppression, and cognitive decline, making cortisol management increasingly important. We discussed these topics with Jonny Bowden, PhD, who holds a Master’s Degree in Psychology and a PhD in Integrative Nutrition. He is also a best-selling author of over a dozen books and a faculty member at the Functional Medicine Coaching Academy.

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The Role of Food Supplements Ingredients in Cortisol Regulation

Cortisol, the body’s primary stress hormone, plays a critical role in managing stress and maintaining homeostasis. Chronic stress and dysregulation of the hypothalamus-pituitary-adrenal axis can lead to health issues like inflammation and metabolic dysfunction. Ingredients like adaptogens, omega-3 fatty acids, and hydrolyzed casein in food supplements may help modulate cortisol levels and improve overall stress resilience.

AUTHOR: Daria Šurić, Mpharm, univ.spec.pharm.

Read More »

STUDY: Gencor’s Levagen®+ Demonstrates Significant Support to Ease Menstrual Discomfort

 Gencor has announced the publication of its recent human clinical study investigating its palmitoylethanolamide (PEA) ingredient, Levagen®+, to be a safe, innovative, and effective supplement to ease acute menstrual discomfort. Menstrual pain, or primary dysmenorrhea (menstrual pain without any underlying pathology), is the most common gynecological condition among women of reproductive age. It is estimated to be the leading cause of chronic pelvic pain globally (World Health Organization). The prevalence rate ranges from 45 to 95% and is linked to restrictions in daily activities, work and school absenteeism, and personal distress. While the primary mechanisms of dysmenorrhea are not fully understood, the main cause of the painful symptoms is attributed to the overproduction of uterine prostaglandins, particularly prostaglandin F2-α (PGF2α) and prostaglandin E2 (PGE2), which peak during the early days of menstruation. Besides their regulatory effects on inflammation, pain, and body temperature, prostaglandin production is also thought to contribute to secondary symptoms of menstrual pain, such as diarrhea, nausea, and vomiting. Moreover, women experiencing dysmenorrhea may show elevated levels of pro-inflammatory mediators and an increased body temperature. Preclinical research suggests that PEA’s primary mechanism of action is to provide relief from occasional discomfort and support a balanced inflammatory response, which may

Read More »

Nearly Half of Type 2 Diabetes Patients Have Micronutrient Deficiencies, New BMJ Review Finds

A new systematic review published in BMJ highlighted the fact that nearly half of patients with type 2 diabetes (T2D) experience micronutrient deficiencies, with women experiencing these deficiencies more frequently than men. Micronutrients are valuable cofactors in glucose metabolic pathways, pancreatic beta cell function, and the insulin signaling cascade, suggesting that their deficiency may contribute to the development of T2D. Micronutrients such as biotin, chromium, thiamine, vitamin D, and vitamin C may have metabolic effects on glucose metabolism. Researchers and physicians have paid little attention to the role of hidden hunger and micronutrient deficiencies in type 2 diabetes. A new systematic review and meta-analysis assessed the prevalence of various micronutrient deficiencies in the T2D patient population reported in 127 published studies (1998-2023), with 52,501 patients in total who met the inclusion and exclusion criteria. Almost half (45.30%) of the T2D population had multiple micronutrient deficiencies, and 40% of patients with diabetic complications had micronutrient deficiencies. The prevalence of vitamin D deficiency was highest (60.45%), followed by magnesium deficiency (41.95%). The next in order was vitamin B12 deficiency in a subgroup of T2D patients on metformin. . Deficiency of these micronutrients is notably prevalent among individuals who have both obesity and

Read More »

Interview Jonny Bowden, PhD Cortisol: Q and A

Consumer interest in cortisol is rising due to growing awareness about the negative effects of chronic stress on physical and mental health, as well as cortisol’s role in stress and weight gain. Elevated cortisol levels contribute to various health issues, including weight gain, immune suppression, and cognitive decline, making cortisol management increasingly important. We discussed these topics with Jonny Bowden, PhD, who holds a Master’s Degree in Psychology and a PhD in Integrative Nutrition. He is also a best-selling author of over a dozen books and a faculty member at the Functional Medicine Coaching Academy.

Read More »

The Role of Food Supplements Ingredients in Cortisol Regulation

Cortisol, the body’s primary stress hormone, plays a critical role in managing stress and maintaining homeostasis. Chronic stress and dysregulation of the hypothalamus-pituitary-adrenal axis can lead to health issues like inflammation and metabolic dysfunction. Ingredients like adaptogens, omega-3 fatty acids, and hydrolyzed casein in food supplements may help modulate cortisol levels and improve overall stress resilience.

AUTHOR: Daria Šurić, Mpharm, univ.spec.pharm.

Read More »