At Ingood by Olga we are curious by nature and we care for the others. Beyond our ingredients, we really want to provide natural and effective solutions useful to everyone. That’s why we have set ourselves the challenge to develop an active ingredient directly titrated in active and stable sulforaphane, an active molecule providing many proven health benefits. Thanks to 20 years of research, we have drawn the best in broccoli.
Broccoli is known for its richness in sulfur compounds and is more specifically the richest crucifer in glucoraphanin, a precursor of sulforaphane. Unfortunately, eating broccoli is not enough to provide the effective dose of sulforaphane. It depends on broccoli quality, storage conditions of the broccoli, ability to hydrolyse glucoraphanin.
Sulforaphane is an isothiocyanate compound found in broccoli. It’s derived from the hydrolysis of its precursor, glucoraphanin, by an enzyme called myrosinase.
Sulfodyne® is the only broccoli seed extract on the market with the stable and active bioavailable form of sulforaphane.1
SULFODYNE®: 3 mechanisms of action
- Antioxidant activity: Sulforaphane is a strong indirect antioxidant thanks to the activation of Nrf2 expression2,3
Anti-inflammatory activity: Sulforaphane reduces inflammation by inducing NF-κB inhibition and Nrf2 expression4,5
- Cellular protection: Sulforaphane has an epigenetic activity that impacts DNA methylation and histone acetylation. Some genes are regulated inducting cellular protection6,7
These 3 mechanisms of action explain the wide range of health benefits of SULFODYNE®.
SULFODYNE® for the detox
The body naturally activates its own defense mechanisms against foreign substances that are toxic to the body, called “xenobiotics” but can only partially neutralize and eliminate them. Sulfodyne® can help the body to eliminate xenobiotics thanks to:8
- Induction of the phase II enzymes
- Reduction of intracellular ROS content
SULFODYNE® for immunity
Since Covid, immunity has been a major concern for customers. Sulfodyne® can play a role in boosting the immune system, both in the preventive phase and in the acute phases, by enhancing the body’s natural defences mechanisms9,10
- Enhancement of the antibody production
- Increase of the phagocytic activity
- Antiviral activity: Reduction of the replication and the propagation of the virus and inhibition of virus both in prevention and in treatment
SULFODYNE® for joints
Joints are complex structures composed of bones, muscles, ligaments, tendons and other tissues. Due to ageing and chronic inflammation, 1,71 billion people are concerned by variable degrees of pain accompanied by stiffness, swelling and loss of joint function.
In case of rheumatoid arthritis, Sulfodyne® can reduce inflammation by decreasing inflammatory markers:11,12
- Decrease of the MMPS and COX-2 expression (cartilage degradation)
- Decrease of the PGE2 production (cartilage joints pain)
- Reduction of NF-kB activity (inflammation pathways)
SULFODYNE® for women’s health
Women’s health is very large and encompasses a number of symptoms, time of life or diseases that have long been ignored by medical research like endometriosis, pre-menstrual syndrome, menopause, etc. Some of these conditions are linked by an uncontrolled inflammation process and the role of sulforaphane, notably through the activation of Nrf2 expression, is gaining interest in the management of some women health issues like endometriosis or premenstrual syndroms (PMS).13
SULFODYNE® for glucose regulation
Control of hyperglycaemia is crucial to prevent and delay diabetes. It is well recognized that careful management of early-stage hyperglycaemia is essential. Sulfodyne® can modulate the expression of Nrf2 which is known to play an important role in preventing the development of diabetes and its complications.14
- Induction of Nrf2 expression
- Reduction in glucose production similar to metformin
Ingood by Olga
Ingood by Olga is the business unit dedicated to ingredients of the Olga group, a family-owned company based in Brittany. Born in 2015, we are daily guided by our purpose: To offer the best of our materials in respect of our ecosystems and with boldness. We produce and offer plant-based ingredients for health, nutrition and food markets. Convinced that everything is good in our materials, we are working for a circular model and we want to bring natural and useful ingredients to everyone promoting a more positive approach to food and societal transition. Beyond our ingredients, we believe in a whole model of sustainable development that we want to share generously around us.
Our mission supports the idea that to do good, we must first do right: for the environment, ecosystems, staff, and customers alike. This holistic approach business dovetails with that of sustainable development, a dynamic to which we are fully committed today, as evidenced by the company’s exemplary ISO 26000 certification (CSR label), one of the highest certifications that can be awarded.
2 Rue Julien Neveu,
35530 Noyal-sur-Vilaine Bretagne 35530, France T. +33 (0)2 99 04 11 11
www.linkedin.com/company/ingood-by-olga/
References:
1 Fahey et al., 2016
2 Briones-Herrena et al., 2018;
3 Ruhee & Suzuki, 2020
4 Ahmed et al., 2016;
5 Ruhee & Suzuki, 2020
6 Li, 2021; Houghton, 2019;
7 Su et al., 2018
8 Munday et al., 2008
9 Thejass & Kuttan, 2006
10 Ordonez et al., 2021
11 Choi et al, 2014
12 Moon et al., 2021
13 Zhou et al., 2019
14 Axelsson et al., 2017
