MartinBauer Nutraceuticals announces the launch of AnnurTriComplex®, a clinically validated branded ingredient designed to support hair strength and natural hair growth without side effects.
Hair thinning is increasingly recognised as a significant aesthetic concern with strong links to self‑perception and psychosocial wellbeing. Published epidemiological data indicate that ~30% – 50% of all women experience hair loss or thinning at some point in their lives. Androgenetic alopecia affects up to 50% of men by age 50, with approximately 30% of men in their twenties already exhibit visible thinning. An estimated 735,000 to 800,000 hair transplant procedures are performed globally, each year, highlighting a growing consumer demand for proactive, healthy and evidence‑based solutions.
For product developers, these trends underscore the need for scientifically substantiated, naturally derived ingredients that support healthy hair while maintaining systemic balance—suitable for both prevention and long‑term use.
Some current treatments are intended exclusively for men, as they reduce dihydrotestosterone (DHT) synthesis, while others promote vasodilation. Both approaches may also present tolerability and compliance issues for certain users or compromise sexual performance.
AnnurTriComplex® offers a botanical alternative focused on supporting follicular activity and hair‑growth. The ingredient is derived from Annurca apples (Malus pumila) cultivated exclusively in the Campania region of southern Italy, protected by “Melannurca Campana PGI” and standardised for oligomeric procyanidins and polyphenols. Pre-clinical and clinical research conducted at the University of Naples, Italy, has documented these apples for their impact on scalp and follicular health, including increased keratin expression and antioxidant protection.
Pre-clinical studies demonstrated that AnnurTriComplex® enhances the hair follicle and reprograms the mitochondria, leading to increased hair follicle activity and upregulation of keratin synthesis. This enables stronger, fuller‑looking hair and sustained growth over time. Complementary in-vivo studies showed reduced hair loss and prolonged active hair growth phase (anagenphase).
The clinical trials support these findings: a randomised, double‑blind study demonstrated the superiority of Annurca apple compared with other apple varieties, and a subsequent trial involving 250 adults with hair loss issues showed that supplementation with 400 mg of AnnurTriComplex® twice daily significantly improved hair‑growth outcomes after 60 days.
“These findings support a positioning for healthy hair growth, strength, thickness and density,” says Dr. Julia Wiebe of MartinBauer Nutraceuticals. “AnnurTriComplex® provides formulators with a clinically effective, natural, food‑derived ingredient that supports follicular health and growth rate helping streamline regulatory positioning while meeting consumer expectations for safety and scientific credibility.”
AnnurTriComplex® features a pleasant natural apple taste, good solubility. Moreover, it is suitable for both, oral and topical applications, enabling brands to deliver comprehensive 360° hair‑health solutions.
Aligned with plant‑based and clean‑label formulation strategies, AnnurTriComplex® is produced through MartinBauer’s proprietary process, which preserves the integrity of the natural apple matrix to ensure optimal bio-accessibility and bioavailability. Its multi‑targeted activity—including antioxidant support, bioactivation of hair‑follicles, and enhanced keratin expression—broadens development opportunities beyond mechanisms traditionally associated with topical vasodilators and without interfering with hormonal balance.
“With increasing consumer focus on appearance and healthy ageing, hair health has become an important area of interest in nutraceutical research,’” Dr. Julia Wiebe concludes. “AnnurTriComplex® offers a clinically substantiated solution with a clear mechanism of action, providing manufacturers with an opportunity to develop differentiated and effective hair health products.”
For more information on AnnurTriComplex®, contact MartinBauer Nutraceuticals or visit www.martin-bauer-nutraceuticals.com.


