The results, which were presented at the world’s leading clinical conference for bone, joint and muscle health, WCO-IOF-ESCEO (4-7 May, Barcelona), highlight the exciting potential of Mobilee® in nutritional solutions targeted towards muscle health, and overall mobility.
The aim of the present research was to evaluate the effect of Mobilee® on muscle health specifically, using in vitro models of health and sarcopenia. Myocytes (muscle cells) were treated with 6 µg/mL digested Mobilee® for 24 hours. Effect in muscle homeostasis (measured by assessing the proliferation and hyperplasia of myocytes) and protection against muscle damage and atrophy were evaluated. The results showed that Mobilee® promoted myocyte hyperplasia (increase in myocyte size) by 7% and myocyte proliferation (production of new cells) by more than 20%. The ingredient also showed an effect against muscle atrophy, muscle damage and cell death in the sarcopenia model.
“We are one of the first organisations to explore the role of hyaluronic acid-rich solutions on muscle health,” says Daniel Martinez-Puig, Head of R&D Human Health, Bioiberica. “Mobilee® is the result of 15-plus years of research and development and is backed by robust scientific research demonstrating its unique benefits in joint and muscle health. This latest evidence points towards its potential to play a supportive role in muscles too; where it may be effective for balancing muscle cell turnover and protecting against common characteristics of sarcopenia.”
Jaume Reguant, Healthcare Director, Bioiberica adds: “Western societies are ageing and there is a progressive rise in the prevalence of muscle disorders, like sarcopenia – which significantly impact an individual’s overall mobility, independence and quality of life. Simultaneously, there is a greater focus on exercise and remaining active, both in younger, healthier populations and older generations. Consumers recognise that good mobility goes beyond looking after joint health alone and they understand that nutritional support can aid their mobility. With this in mind, it’s an exciting time to innovate with a premium, easy-to-formulate ingredient, like Mobilee®. It taps into multiple market trends and consumer preferences – from the active nutrition movement to rising demand for multi-ingredient solutions that bring holistic health benefits, as well as increasing appetite for convenient, low dose and science-backed products.”
Mobilee® is the first hyaluronic acid matrix ingredient available for innovation in the mobility market; demonstrated to support joint and muscle health at a low dose of only 80 mg/day. A patented ingredient made up of three naturally-occurring components – hyaluronic acid (60-75%), polysaccharides and collagen – Mobilee® is powering new advancements in the joint and muscle health and mobility categories. It is suitable for dietary supplement and functional food applications.