The Gut-Skin Axis: Where Does Acne Begin?
Acne vulgaris is increasingly recognized not merely as a localized skin disorder, but as a complex systemic condition influenced by hormonal, metabolic, and microbial factors. Emerging evidence highlights the pivotal role of insulin signaling and gut microbiome dysbiosis in driving inflammation and sebaceous activity. This evolving perspective supports a shift toward integrative therapeutic strategies targeting the gut–skin axis.
Authors: Emanuela Krpan, MSc, Master in Nutrition.
Paola Pavačić, MSc. Microbiome in Health and Disease